Kathleen Sullivan, MD, PhD is the Chief of Allergy and Immunology at Children's Hospital of Philadelphia and a member of the IDF Physician Advisory Committee. She put together a video update focused on antibodies. This video sets out to answer three questions:
- Are all antibodies good?
- Why can’t we just make a vaccine - any vaccine - and get going?
- Are antibodies after a vaccine the same as after natural infection?
Types of Antibodies (Most vaccines induce an IgG response)
- IgG (IgG1 IgG2 IgG3 IgG4) neutralization, memory
- IgA mucous membranes
- IgM high avidity, first responder
- IgD mucous membranes, tolerance
- IgE Helminth infections
What do we know about antibodies to SARS CoV2?
- Convalescent plasma seems to work
- Antibodies seem to peak at about 2-3 weeks after infection
- Sicker patients make more antibodies
- Antibodies decline over two years