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Since You Asked: Question & Answer (October 2017)

These Questions & Answers originally appeared in the IDF monthly e-newsletter, Primary Immune Tribune. Click here to subscribe.

Question: 
I have been diagnosed with active Epstein Barr Virus (EBV) Mono again, one year after my last confirmed diagnosis. I was told that the IVIG medicine can cause the body to go into an active state of EBV mono. Is this a possible side effect?

Answer: 
No, EBV Mono is not a complication of IVIG treatment. The resurgence of Mono could be related to your current state of health. EBV stays with us after the initial infection regardless of how severe the mono is, living long in our lymphocytes. Sometimes the EBV reactivates itself from the quiet state, and causes symptoms. This is sometimes referred to as chronic mono.  Many things can reactive the EBV from the quiet state, but we are not aware that IVIG does this.

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