| Immune Deficiency Foundation

Understanding primary immunodeficiency (PI)
Understanding PI
The more you understand about primary immunodeficiency (PI), the better you can live with the disease or support others in your life with PI. Learn more about PI, including the various diagnoses and treatment options.
Learn more about PI
Living with PI
Living with PI
Living with primary immunodeficiency (PI) can be challenging, but you’re not alone—many people with PI lead full and active lives. With the right support and resources, you can, too.
Learn more about living with PI
Get involved
Get involved
Be a hero for those with PI. Change lives by promoting primary immunodeficiency (PI) awareness and taking action in your community through advocacy, donating, volunteering, or fundraising.
Get involved today
Advancing research and clinical care
Advancing research and clinical care
Whether you’re a clinician, researcher, or an individual with primary immunodeficiency (PI), IDF has resources to help you advance the field. Get details on surveys, grants, and clinical trials.
View resource details

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IDF video

Gene editing for X-linked agammaglobulinemia (XLA): 2024 PI Conference

August 05, 2024

IDF video

The future is now: preparing for transition to adult care: 2024 PI Conference

August 05, 2024

IDF video

Dermatology issues in the PI patient: 2024 PI Conference

August 05, 2024

IDF video

Translating microbiology of infections into genetics of immunology: 2024 PI Conference

August 05, 2024

IDF video

Hyper IgM syndrome: T cell markers as a guide to treatment & severity: 2024 PI Conference

August 01, 2024

Dermatology and PI

Conference session explores susceptibility to skin conditions in PI

August 01, 2024

IDF video

PI & aging: 2024 PI Conference

August 01, 2024

Watch 2024 PI Conference sessions

Missed a session or want a refresher? 2024 PI Conference session recordings are now available!

Jax and Lincoln Ramirez in pool

Boy with IPEX treated with gene therapy at Stanford University

Bold Conversations: Social determinants of health

Listen to podcast

Immune Deficiency Foundation
7550 Teague Road, Suite 220
Hanover, Maryland 21076

P: 410-321-6647