Treatment
Learn how primary immunodeficiency (PI) is treated, from recurring treatments like immunoglobulin (Ig) replacement therapy to long-lasting treatments like hematopoietic stem cell transplant (HSCT).
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Understanding primary immunodeficiency (PI)
Understanding PI
The more you understand about primary immunodeficiency (PI), the better you can live with the disease or support others in your life with PI. Learn more about PI, including the various diagnoses and treatment options.
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Living with PI
Living with PI
Living with primary immunodeficiency (PI) can be challenging, but you’re not alone—many people with PI lead full and active lives. With the right support and resources, you can, too.
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Get involved
Get involved
Be a hero for those with PI. Change lives by promoting primary immunodeficiency (PI) awareness and taking action in your community through advocacy, donating, volunteering, or fundraising.
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Advancing research and clinical care
Advancing research and clinical care
Whether you’re a clinician, researcher, or an individual with primary immunodeficiency (PI), IDF has resources to help you advance the field. Get details on surveys, grants, and clinical trials.
Immunoglobulin (Ig) replacement therapy
Ig replacement therapy provides antibodies that help prevent infection in those with antibody deficiencies.
Expert discussion: Ig therapy and long COVID-19
Join us for a discussion on February 19 at 7 pm ET exploring a familiar treatment in a new context: how immunoglobulin (Ig) therapy works against Long COVID-19.
Hematopoietic stem cell transplant (HSCT)
When primary immunodeficiency is likely to cause significant harm or death, HSCT, more commonly known as a bone marrow transplant (BMT), may be the best treatment option.
Read about HSCT
Gene therapy
Gene therapy is in clinical trials for several types of PI and offers an alternative to HSCT when a suitable donor is not available.
Learn about gene therapy
Explore treatments for specific types of PI
Ig replacement therapy, HSCT, and gene therapy are not the only treatments for PI, some types of PI have treatments specific to them. Explore our pages on different types of PI to learn about specific treatments.
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