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Whether you are someone living with PI, a caregiver, or a healthcare professional, you’ll find articles, videos, podcasts, and more to help deepen your understanding of PI.

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Chapter 13: Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked (IPEX) Syndrome

June 30, 2019
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Chapter 14: CTLA-4 Haploinsufficiency and LBRA Deficiency

June 30, 2019
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Chapter 15: Diseases of Immune Dysregulation: STAT1 and STAT3 Gain of Function

June 30, 2019
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Chapter 16: Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy and Autoimmune Polyglandular Syndrome Type-1

June 30, 2019
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Chapter 17: Autoimmune Lymphoproliferative Syndrome and Related Disorders

June 30, 2019
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Chapter 18: Hemophagocytic Lymphohistiocytosis and EBV Susceptibility

June 30, 2019
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Chapter 19: Immune Dysregulation, Enteropathy, and Colitis

June 30, 2019
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Chapter 20: Hyper IgE Syndromes (HIES): STAT3 Loss of Function, DOCK8 Deficiency and Others

June 30, 2019
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Chapter 21: Chronic Granulomatous Disease and Other Phagocyte Disorders, Leukocyte Adhesion Deficiency and Neutropenia

June 30, 2019
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Chapter 22: Complement Deficiencies

June 30, 2019
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Chapter 23: Innate Immune Defects

June 30, 2019
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Chapter 24: Inheritance

June 30, 2019
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Chapter 25: Laboratory Tests

June 30, 2019
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Chapter 26: Newborn Screening

June 30, 2019
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Chapter 27: Infections in People with PI: Antibiotic and Antifungal Therapy

June 30, 2019
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Chapter 28: Immunoglobulin (Ig) Replacement Therapy

June 30, 2019
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Chapter 29: Hematopoietic Stem Cell Transplantation

June 30, 2019
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Chapter 30: Gene Therapy

June 30, 2019

What is PI?

Learn the signs and symptoms of PI and when it might be time to ask your doctor about it.

Learn about PI

Get support

IDF coordinates support groups, events, and one-on-one connections, so you never need to feel alone.

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Ask IDF

Getting answers can help create peace of mind. Ask us anything and we'll consult with experts.

Specialists can be located online through the IDF Clinician Finder. (Please note, if no results populate, increase the distance from your address. You can also search by your state).

Please note the following important information about the list of specialists:

  • These clinicians have voluntarily reported to IDF that they diagnose, treat, and manage patients with primary immunodeficiency (PI). Please know that IDF does not verify these reports.
  • This is not a referral. IDF does not recommend one clinician or medical facility over another or refer patients to a particular provider.
  • It is your responsibility or that of your legal guardian to evaluate, select and engage a clinician or facility, given your insurance coverage and other circumstances, to help you manage your PI. 
    There might be other clinicians at each facility that also treat PI.

Questions to ask while evaluating a clinician or facility:

  • Do you accept my insurance?
  • Do you diagnose and treat patients with primary immunodeficiency diseases? (If already diagnosed, name the PI.)
  • How many patients with primary immunodeficiencies are treated at your facility?

For those receiving Ig replacement therapy:

  • Do you prescribe IVIG and SCIG?
  • Do you prescribe more than one brand of immunoglobulin?
  • Do you offer patients receiving IVIG the option of receiving their infusion in a medical or home setting?

Some patients also find physicians through our Get Connected Groups or IDF Friends

Our virtual education programs are recorded and uploaded to our website resource library and YouTube page. You can view our webinars only via our YouTube webinars playlist.