Understanding primary immunodeficiency (PI)
Understanding PI
The more you understand about primary immunodeficiency (PI), the better you can live with the disease or support others in your life with PI. Learn more about PI, including the various diagnoses and treatment options.
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Living with PI
Living with PI
Living with primary immunodeficiency (PI) can be challenging, but you’re not alone—many people with PI lead full and active lives. With the right support and resources, you can, too.
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Advancing research and clinical care
Advancing research and clinical care
Whether you’re a clinician, researcher, or an individual with primary immunodeficiency (PI), IDF has resources to help you advance the field. Get details on surveys, grants, and clinical trials.
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Moesin deficiency

Related gene: MSN

Inheritance pattern: X-linked

Moesin deficiency is an X-linked immunodeficiency associated with lymphopenia, neutropenia, and recurrent bacterial infections. Prolonged or severe varicella virus infections have been described in several affected individuals. Eczema and autoimmune manifestations, including thrombocytopenia, have been described. Use of antibiotic prophylaxis, immunoglobulin (Ig) replacement therapy, and granulocyte colony-stimulating factor (GCSF) should be strongly considered. Hematopoietic stem cell transplant (HSCT) may also be a consideration.

Read the latest research

Learn more about combined immune deficiencies.

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Diagnosis

Combined immune deficiency

This page contains general medical and/or legal information that cannot be applied safely to any individual case. Medical and/or legal knowledge and practice can change rapidly. Therefore, this page should not be used as a substitute for professional medical and/or legal advice. Additionally, links to other resources and websites are shared for informational purposes only and should not be considered an endorsement by the Immune Deficiency Foundation.

Adapted from the IDF Patient & Family Handbook for Primary Immunodeficiency Diseases, Sixth Edition.
Copyright ©2019 by Immune Deficiency Foundation, USA