Skip to main content
IDF logo

Moesin deficiency

Related gene: MSN

Inheritance pattern: X-linked

Moesin deficiency is an X-linked immunodeficiency associated with lymphopenia, neutropenia, and recurrent bacterial infections. Prolonged or severe varicella virus infections have been described in several affected individuals. Eczema and autoimmune manifestations, including thrombocytopenia, have been described. Use of antibiotic prophylaxis, immunoglobulin (Ig) replacement therapy, and granulocyte colony-stimulating factor (GCSF) should be strongly considered. Hematopoietic stem cell transplant (HSCT) may also be a consideration.

Read the latest research

Learn more about combined immune deficiencies.

This page contains general medical and/or legal information that cannot be applied safely to any individual case. Medical and/or legal knowledge and practice can change rapidly. Therefore, this page should not be used as a substitute for professional medical and/or legal advice.

Adapted from the IDF Patient & Family Handbook for Primary Immunodeficiency Diseases, Sixth Edition 
Copyright ©2019 by Immune Deficiency Foundation, USA