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Whether you are someone living with PI, a caregiver, or a healthcare professional, you’ll find articles, videos, podcasts, and more to help deepen your understanding of PI.

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Cancer risk in primary immunodeficiency (PI): Lymphoma, screening, and treatment explained

December 02, 2025
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How FOXP3 changed immunology: Tregs, IPEX, and the Nobel Prize explained

November 19, 2025
Podcast artwork which reads "Bold conversations: Exploring the realities of health access with Dr. Nicole Rochester."

Bold Conversations: Food Justice with Dr. Jennifer Oliver

November 03, 2025
thumbnail for the ChronicXTwenties podcast which features three circles of Immune Deficiency Foundation colors, and the text "young adulthood, rare disease, and the joy you deserve".

ChronicXTwenties: College and mental health roundtable

September 22, 2025
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Foundation Focus | August 2025

August 25, 2025
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Lunch and Learn: HLH with Dr. Michael Jordan

August 21, 2025
Undiagnosed podcast thumbnail with person walking in shadow toward light. Text in corner reading "Stories of the long journey to PI diagnosis".

Undiagnosed: The wounds that won't close

August 19, 2025
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Foundation Focus | July 2025

July 29, 2025
Podcast artwork which reads "Bold conversations: Exploring the realities of health access with Dr. Nicole Rochester."

Bold Conversations: Misinformation with Dr. Cynthia Baur

July 23, 2025
thumbnail for the ChronicXTwenties podcast which features three circles of Immune Deficiency Foundation colors, and the text "young adulthood, rare disease, and the joy you deserve".

ChronicXTwenties: Demystifying advocacy

July 17, 2025
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Foundation Focus: June 2025 update with CEO Jorey Berry

June 30, 2025
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Lunch & Learn: Understanding genetic variants in APDS

June 10, 2025
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Jorey's monthly wrap-up: May 2025

May 29, 2025
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Problems in practice: Insurance with Dr. Marcus Shaker

May 06, 2025
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Living well with PI: Impact of federal policy changes on the PI community

April 24, 2025
Podcast artwork which reads "Bold conversations: Exploring the realities of health access with Dr. Nicole Rochester."

Bold Conversations: The elephant in the exam room

April 21, 2025
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Decoding PI: The science of gene therapy ​and gene editing

April 07, 2025
Undiagnosed podcast thumbnail with person walking in shadow toward light. Text in corner reading "Stories of the long journey to PI diagnosis".

Undiagnosed: Gaslit and Gatekept

March 26, 2025

What is PI?

Learn the signs and symptoms of PI and when it might be time to ask your doctor about it.

Learn about PI

Get support

IDF coordinates support groups, events, and one-on-one connections, so you never need to feel alone.

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Ask IDF

Getting answers can help create peace of mind. Ask us anything and we'll consult with experts.

Specialists can be located online through the IDF Clinician Finder. (Please note, if no results populate, increase the distance from your address. You can also search by your state).

Please note the following important information about the list of specialists:

  • These clinicians have voluntarily reported to IDF that they diagnose, treat, and manage patients with primary immunodeficiency (PI). Please know that IDF does not verify these reports.
  • This is not a referral. IDF does not recommend one clinician or medical facility over another or refer patients to a particular provider.
  • It is your responsibility or that of your legal guardian to evaluate, select and engage a clinician or facility, given your insurance coverage and other circumstances, to help you manage your PI. 
    There might be other clinicians at each facility that also treat PI.

Questions to ask while evaluating a clinician or facility:

  • Do you accept my insurance?
  • Do you diagnose and treat patients with primary immunodeficiency diseases? (If already diagnosed, name the PI.)
  • How many patients with primary immunodeficiencies are treated at your facility?

For those receiving Ig replacement therapy:

  • Do you prescribe IVIG and SCIG?
  • Do you prescribe more than one brand of immunoglobulin?
  • Do you offer patients receiving IVIG the option of receiving their infusion in a medical or home setting?

Some patients also find physicians through our Get Connected Groups or IDF Friends

Our virtual education programs are recorded and uploaded to our website resource library and YouTube page. You can view our webinars only via our YouTube webinars playlist.