Unspecified hypogammaglobulinemia
Related gene: Unknown
Inheritance pattern: Unknown
Unspecified hypogammaglobulinemia, also known as unspecified antibody deficiency or idiopathic primary hypogammaglobulinemia, describes an individual with one or more deficiencies of IgG, IgA and/or IgM serum immunoglobulins who does not meet the diagnostic criteria for other antibody deficiencies. In general, these patients do not have an impaired ability to produce adequate levels of antibodies against vaccine antigens. In some patients, unspecified hypogammaglobulinemia may simply be a physiologic variant without any clinical significance. However, it may indicate a developing immunodeficiency and should be monitored, particularly if the patient begins to develop frequent and/or severe infections.
