Skip to main content
IDF logo
family together

You are not alone

Primary immunodeficiency (PI) doesn’t have to feel isolating.

Double your impact on Giving Tuesday

This Giving Tuesday double your impact and join our year-round mission to transform lives. Your donation powers breakthrough research, vital support services, and advocacy for the immunocompromised community. Make your matched gift now.

Host a screening of IDF's new documentary

Witness the impossible decisions faced by those living with primary immunodeficiency (PI) disorders. Host a private screening of Compromised: Life Without Immunity to experience the resilience, hope, and determination of the PI community. And know that your hosted event can be two people or 100+!

Watch the film

pi documentary promotional graphic

2025 Advocacy Day & Young Advocates Academy

Every treatment. Every insurance battle. Every late diagnosis. These aren't just challenges – they're reasons to speak up. Join IDF Advocacy Day and Young Advocates Academy in D.C. April 30-May 1, 2025. All expenses covered.

Three individuals standing in front of the United States Capitol.

How well do you know your immune system?

Take our self-assessment to find out if your symptoms could point to a primary immunodeficiency (PI). It’s an informative way to gather insights that you can discuss with your healthcare provider.

taking an online quiz

Let us guide you.

If you are living with PI, think you might have PI, are a caregiver, a healthcare professional, or are just looking to learn more we can help. 

Who is the Immune Deficiency Foundation?

IDF transforms the lives of tens of thousands each year*

Candid Seal Platinum 2023
Charity Navigator logo

822,098

unique visitors to the IDF website to access resources, information, and connection. 

3,195

healthcare professionals learned more about PI diagnosis and treatment.

30,320

individuals living with PI received educational resources and support.

*statistics based on 2023 Community Impact Report

Join an IDF event

Learn more about all the ways to learn, connect, and engage with IDF, whether online and in person.

group of children and adults in a park

Stay informed 

Browse the latest news articles, videos, and podcasts to find the most up-to-date information about advancements in PI treatments, portrayal in the media, and other IDF efforts.