The Patient & Family Handbook for Primary Immunodeficiency, Seventh Edition Preview, contains information about primary immunodeficiencies (PIs; also known as inborn errors of immunity), including symptoms, how they are diagnosed, treatments, and everyday life.
Note that this preview edition contains the following chapters updated from the Patient & Family Handbook for Primary Immunodeficiency Diseases, Sixth Edition. Additional chapters will be released as part of the final seventh edition.
Table of contents
Understanding PI
- Chapter 1: Primary immunodeficiency and your immune system.
- Chapter 2: Genetics.
Diagnosis
- Chapter 3: Laboratory testing.
- Chapter 4: Genetic testing.
- Chapter 5: Newborn screening.
Treatment
- Chapter 6: Preventative antibiotics and other antimicrobials.
- Chapter 7: Immunoglobulin replacement therapy.
- Chapter 8: Hematopoietic stem cell transplantation.
- Chapter 9: Gene therapy.
Living with PI
- Chapter 10: Nurturing physical and mental health.
- Chapter 11: Vaccines.
- Chapter 12: Navigating health insurance.
- Chapter 13: Thriving in the workplace.
- Chapter 14: Respiratory health.
- Chapter 15: Digestive and liver health.
- Chapter 16: Other body systems.
- Chapter 17: Fertility and pregnancy.
- Chapter 18: Caring for children and adolescents.
- Chapter 19: Senior adults.
- Chapter 20: Participating in clinical research.
Appendix: Medical specialties cheat sheet
Glossary
References
Copyright © 2026, Immune Deficiency Foundation, USA.
Readers may redistribute this guide to other individuals for non-commercial use, provided the text, HTML code, and this notice remain intact and unaltered in any way. The Patient & Family Handbook for Primary Immunodeficiency, seventh edition preview© may not be resold, reprinted, or redistributed for compensation of any kind without prior written permission from the Immune Deficiency Foundation.

