Children with CGD are usually healthy at birth. The features of CGD generally first appear in childhood, although some individuals do not show symptoms until later in life.
Children with CGD are usually healthy at birth. The most common CGD infection in infancy is a skin or bone infection with the bacteria Serratia marcescens, so any infant with this particular infection should be tested for CGD. In fact, any infant or child with a significant infection with any of the organisms previously listed should be tested for CGD.
Any patient of any age with a CGD type infection (Staphylococcus aureus, Burkholderia cepacia complex, Serratia marcescens, Nocardia and Aspergillus) should be tested for CGD.
There are six different genetic kinds of CGD. The most common form is called X-linked, because it is on the X chromosome (70% of cases in the U.S) and affects almost only boys.