| Immune Deficiency Foundation

Understanding primary immunodeficiency (PI)
Understanding PI
The more you understand about primary immunodeficiency (PI), the better you can live with the disease or support others in your life with PI. Learn more about PI, including the various diagnoses and treatment options.
Learn more about PI
Living with PI
Living with PI
Living with primary immunodeficiency (PI) can be challenging, but you’re not alone—many people with PI lead full and active lives. With the right support and resources, you can, too.
Learn more about living with PI
Get involved
Get involved
Be a hero for those with PI. Change lives by promoting primary immunodeficiency (PI) awareness and taking action in your community through advocacy, donating, volunteering, or fundraising.
Get involved today
Advancing research and clinical care
Advancing research and clinical care
Whether you’re a clinician, researcher, or an individual with primary immunodeficiency (PI), IDF has resources to help you advance the field. Get details on surveys, grants, and clinical trials.
View resource details

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thumbnail for the ChronicXTwenties podcast which features three circles of Immune Deficiency Foundation colors, and the text "young adulthood, rare disease, and the joy you deserve".

ChronicxTwenties: Heartbreakingly beautiful (Part 1)

October 23, 2024

Listen to podcast

Gloved hand uses tweezers to remove a section of a paper drawing of DNA.

Gene therapy makes headway in PI treatment

October 17, 2024

Blaese awardee targets diagnosis and treatment of Evans syndrome

October 10, 2024

Woman getting a shot in her upper arm from healthcare provider.

Ensuring clinical trial diversity for emerging rare disease therapies

October 08, 2024

Bold conversations thumbnail

Bold Conversations: CGD and medical immigration with Susanna Raj

October 08, 2024

Listen to podcast

image of nurse checking a patient's heart rate with text "Decoding PI: Protecting yourself against covid, flu, and RSV.

Decoding PI: Protecting yourself against covid, flu, and RSV

October 07, 2024

Girl walking with a suitcase

Traveling with PI checklist

October 04, 2024

Person performing lab work

Laboratory tests, patient story critical in diagnosing PI

October 03, 2024

Doctor with X-ray

Address lung disease early with primary immunodeficiency

September 26, 2024

fall advocate 2024

Fall 2024 IDF ADVOCATE newsletter

September 25, 2024

Immune Deficiency Foundation
7550 Teague Road, Suite 220
Hanover, Maryland 21076

P: 410-321-6647