| Immune Deficiency Foundation

Understanding primary immunodeficiency (PI)
Understanding PI
The more you understand about primary immunodeficiency (PI), the better you can live with the disease or support others in your life with PI. Learn more about PI, including the various diagnoses and treatment options.
Learn more about PI
Living with PI
Living with PI
Living with primary immunodeficiency (PI) can be challenging, but you’re not alone—many people with PI lead full and active lives. With the right support and resources, you can, too.
Learn more about living with PI
Get involved
Get involved
Be a hero for those with PI. Change lives by promoting primary immunodeficiency (PI) awareness and taking action in your community through advocacy, donating, volunteering, or fundraising.
Get involved today
Advancing research and clinical care
Advancing research and clinical care
Whether you’re a clinician, researcher, or an individual with primary immunodeficiency (PI), IDF has resources to help you advance the field. Get details on surveys, grants, and clinical trials.
View resource details

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2025 IDF research grant application

January 01, 2025

Mathilda von Guttenberg near water

UCLA student with CVID studies how mindset shapes health outcomes

December 19, 2024

headset and stack of books

Q&A: Protecting yourself against COVID, flu, and RSV

December 12, 2024

Listen to podcast

Decoding PI: Unraveling the GI connection

December 12, 2024

Listen to podcast

Older man and kid show off their band aids after getting vaccine.

Vaccines protect the immunocompromised

December 12, 2024

Man with mask grocery shopping.

Masks protect the immunocompromised

December 12, 2024

son kisses mother on cheek

Study confirms many X-linked CGD carriers experience symptoms

December 11, 2024

Nurse examining patient with the text "Decoding PI: Unraveling the GI Connection".

Decoding PI: Unraveling the GI connection

December 06, 2024

Bob LeBien and family

Bob LeBien’s leadership a guiding force for IDF and IPOPI

December 04, 2024

Child receiving vaccine

Statement regarding the leadership of the U.S. Department of Health and Human Services

December 02, 2024

Immune Deficiency Foundation
7550 Teague Road, Suite 220
Hanover, Maryland 21076

P: 410-321-6647