| Immune Deficiency Foundation

Understanding primary immunodeficiency (PI)
Understanding PI
The more you understand about primary immunodeficiency (PI), the better you can live with the disease or support others in your life with PI. Learn more about PI, including the various diagnoses and treatment options.
Learn more about PI
Living with PI
Living with PI
Living with primary immunodeficiency (PI) can be challenging, but you’re not alone—many people with PI lead full and active lives. With the right support and resources, you can, too.
Learn more about living with PI
Get involved
Get involved
Be a hero for those with PI. Change lives by promoting primary immunodeficiency (PI) awareness and taking action in your community through advocacy, donating, volunteering, or fundraising.
Get involved today
Advancing research and clinical care
Advancing research and clinical care
Whether you’re a clinician, researcher, or an individual with primary immunodeficiency (PI), IDF has resources to help you advance the field. Get details on surveys, grants, and clinical trials.
View resource details

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Langenhop kids sitting on a bench and smiling

Siblings treated for LAD-1 with gene therapy remain healthy

August 30, 2024

IDF 2024 research grantees Drs. Emily Harris, David Nguyen, Alexandra Martinson, and Laruen Meyer.

Grantees probe biology to aid primary immunodeficiency diagnosis

August 29, 2024

Bold Conversations thumbnail with an image of Dr. Nicole Rochester

Bold Conversations: Inclusion in practice at the 2024 PI Conference

August 28, 2024

Listen to podcast

Frank final

85-year-old with PI celebrates 500th immunoglobulin infusion

August 23, 2024

Hospital emergency entrance.

I Am A Transplant Patient emergency card

August 22, 2024

beach scene

New documentary film released

August 20, 2024

Read press release

2023 Annual Report

2023 Annual Report

August 19, 2024

IDF video

Overview of WHIM syndrome: 2024 PI Conference

August 05, 2024

IDF video

Serenity within: stress management for PI: 2024 PI Conference

August 05, 2024

IDF video

Hyper IgM overview: 2024 PI Conference

August 05, 2024

Immune Deficiency Foundation
7550 Teague Road, Suite 220
Hanover, Maryland 21076

P: 410-321-6647