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Understanding primary immunodeficiency (PI)
Understanding PI
The more you understand about primary immunodeficiency (PI), the better you can live with the disease or support others in your life with PI. Learn more about PI, including the various diagnoses and treatment options.
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Living with PI
Living with PI
Living with primary immunodeficiency (PI) can be challenging, but you’re not alone—many people with PI lead full and active lives. With the right support and resources, you can, too.
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Get involved
Get involved
Be a hero for those with PI. Change lives by promoting primary immunodeficiency (PI) awareness and taking action in your community through advocacy, donating, volunteering, or fundraising.
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Advancing research and clinical care
Advancing research and clinical care
Whether you’re a clinician, researcher, or an individual with primary immunodeficiency (PI), IDF has resources to help you advance the field. Get details on surveys, grants, and clinical trials.
Browse the latest news articles, videos, and podcasts to find the most up-to-date information about advancements in PI treatments, portrayal in the media, and other IDF efforts.
Related Resources
Foundation to follow medical societies' vaccine schedules in light of ACIP hepatitis B decision
December 09, 2025
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PhD student with PI works to improve cancer care
December 04, 2025
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What are primary immune regulatory disorders (PIRD)? Symptoms, diagnosis, and treatment explained
December 03, 2025
Watch video
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