| Immune Deficiency Foundation

Understanding primary immunodeficiency (PI)
Understanding PI
The more you understand about primary immunodeficiency (PI), the better you can live with the disease or support others in your life with PI. Learn more about PI, including the various diagnoses and treatment options.
Learn more about PI
Living with PI
Living with PI
Living with primary immunodeficiency (PI) can be challenging, but you’re not alone—many people with PI lead full and active lives. With the right support and resources, you can, too.
Learn more about living with PI
Get involved
Get involved
Be a hero for those with PI. Change lives by promoting primary immunodeficiency (PI) awareness and taking action in your community through advocacy, donating, volunteering, or fundraising.
Get involved today
Advancing research and clinical care
Advancing research and clinical care
Whether you’re a clinician, researcher, or an individual with primary immunodeficiency (PI), IDF has resources to help you advance the field. Get details on surveys, grants, and clinical trials.
View resource details

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Nurse examining patient with text: "Decoding PI: The science of gene therapy and gene editing".

Decoding PI: The science of gene therapy and gene editing

thumbnail for the ChronicXTwenties podcast which features three circles of Immune Deficiency Foundation colors, and the text "young adulthood, rare disease, and the joy you deserve".

ChronicXTwenties: Transitioning from pediatric to adult care with Riley and Nick

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Rare Disease Diversity Coalition

https://www.rarediseasediversity.org/

National Hispanic Health Foundation

https://www.nhmafoundation.org/

Association of Minority Health Professions Schools, Inc.

https://amhps.org/

National Pharmaceutical Association

https://nationalpharmaceuticalassociation.org/

Health HIV

https://healthhiv.org/

Tired of being sick? It could be your immune system.

Our assessment tool helps identify potential primary immunodeficiency patterns. Take the first step toward answers.

Researcher studying DNA

Study uses genomic screening to look for PI in newborns

February 27, 2025

Bold Conversations: Health insurance

February 21, 2025

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Immune Deficiency Foundation
7550 Teague Road, Suite 220
Hanover, Maryland 21076

P: 410-321-6647