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Whether you are someone living with PI, a caregiver, or a healthcare professional, you’ll find articles, videos, podcasts, and more to help deepen your understanding of PI.

Gloved hand uses tweezers to remove a section of a paper drawing of DNA.

Gene therapy makes headway in PI treatment

October 17, 2024
Headshot of Dr. Emily Harris.

Blaese awardee targets diagnosis and treatment of Evans syndrome

October 10, 2024
Woman getting a shot in her upper arm from healthcare provider.

Ensuring clinical trial diversity for emerging rare disease therapies

October 08, 2024
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2025 IDF research grant application

October 08, 2024
IDF 2024 research grantees Drs. Emily Harris, David Nguyen, Alexandra Martinson, and Laruen Meyer.

Foundation announces research seed grants

September 20, 2024
IDF 2024 research grantees Drs. Emily Harris, David Nguyen, Alexandra Martinson, and Laruen Meyer.

Grantees probe biology to aid primary immunodeficiency diagnosis

August 29, 2024
IDF video

Meet the researchers: Clinical trials update: 2024 PI Conference

August 05, 2024
Doctor speaking with girl and her parent.

Mavorixafor approved for treating WHIM syndrome

May 02, 2024
Person using pen and clipboard to fill out paperwork.

Autoimmune diagnoses may obscure primary immunodeficiency

April 24, 2024
Title slide for 2023 National Patient Survey report.

2023 National Patient Survey report

April 24, 2024
Dr. Megan Cooper in her laboratory.

Discovery of new PI shows value of grants for exploratory research

December 08, 2023
Woman with her hand to her head and article title.

Study shows CVID patients at higher risk for neurologic issues

September 15, 2023
A woman and a health care professional have a discussion.

Clinical trial explores biologic treatment for CVID lung condition

August 31, 2023
A microscopic view of blood cells and viruses.

Study examines procedure to treat severe CGD infections

July 25, 2023
Person typing on a computer

PI research grants span diagnosis, T cell biology, and new treatments

June 02, 2023
Gene editing strategy for XLA with Dr. Donald Kohn's headshot.

Blaese awardee is developing a gene editing strategy to treat XLA

June 02, 2023
Person typing on a computer

Primary immunodeficiency patient registry moves into a new era

May 09, 2023

What is PI?

Learn the signs and symptoms of PI and when it might be time to ask your doctor about it.

Learn about PI

Get support

IDF coordinates support groups, events, and one-on-one connections, so you never need to feel alone.

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Ask IDF

Getting answers can help create peace of mind. Ask us anything and we'll consult with experts.

Specialists can be located online through the IDF Clinician Finder. (Please note, if no results populate, increase the distance from your address. You can also search by your state).

Please note the following important information about the list of specialists:

  • These clinicians have voluntarily reported to IDF that they diagnose, treat, and manage patients with primary immunodeficiency (PI). Please know that IDF does not verify these reports.
  • This is not a referral. IDF does not recommend one clinician or medical facility over another or refer patients to a particular provider.
  • It is your responsibility or that of your legal guardian to evaluate, select and engage a clinician or facility, given your insurance coverage and other circumstances, to help you manage your PI. 
    There might be other clinicians at each facility that also treat PI.

Questions to ask while evaluating a clinician or facility:

  • Do you accept my insurance?
  • Do you diagnose and treat patients with primary immunodeficiency diseases? (If already diagnosed, name the PI.)
  • How many patients with primary immunodeficiencies are treated at your facility?

For those receiving Ig replacement therapy:

  • Do you prescribe IVIG and SCIG?
  • Do you prescribe more than one brand of immunoglobulin?
  • Do you offer patients receiving IVIG the option of receiving their infusion in a medical or home setting?

Some patients also find physicians through our Get Connected Groups or IDF Friends

Our virtual education programs are recorded and uploaded to our website resource library and YouTube page. You can view our webinars only via our YouTube webinars playlist.