| Immune Deficiency Foundation

Understanding primary immunodeficiency (PI)
Understanding PI
The more you understand about primary immunodeficiency (PI), the better you can live with the disease or support others in your life with PI. Learn more about PI, including the various diagnoses and treatment options.
Learn more about PI
Living with PI
Living with PI
Living with primary immunodeficiency (PI) can be challenging, but you’re not alone—many people with PI lead full and active lives. With the right support and resources, you can, too.
Learn more about living with PI
Get involved
Get involved
Be a hero for those with PI. Change lives by promoting primary immunodeficiency (PI) awareness and taking action in your community through advocacy, donating, volunteering, or fundraising.
Get involved today
Advancing research and clinical care
Advancing research and clinical care
Whether you’re a clinician, researcher, or an individual with primary immunodeficiency (PI), IDF has resources to help you advance the field. Get details on surveys, grants, and clinical trials.
View resource details

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Gamunex-C, GammaKed lots withdrawn

November 06, 2025

Thumbnail reading "Decoding PI: The link between PI and cancer"

Decoding PI: The link between PI and cancer

November 06, 2025

Ig graphic

Immunoglobulin product booklet

November 05, 2025

Becky Lenning and family at Christmas

Set boundaries for a safe holiday season

November 04, 2025

Podcast artwork which reads "Bold conversations: Exploring the realities of health access with Dr. Nicole Rochester."

Bold Conversations: Food Justice with Dr. Jennifer Oliver

November 03, 2025

Listen to podcast

Ariell with family

Arielle’s PI journey led her to advocating for the immunocompromised

October 31, 2025

Older adult couple looking through paperwork.

Update: Compare costs and coverage with Medicare plans

October 30, 2025

'Compromised' documentary movie graphic

Documentary film earns film festival recognition

October 16, 2025

Read press release

Katherine Taylor with dogs mural

Muralist with CVID spreads joy through her art

October 15, 2025

Immunoglobulin replacement therapy prior authorization checklist

October 01, 2025

Immune Deficiency Foundation
7550 Teague Road, Suite 220
Hanover, Maryland 21076

P: 410-321-6647