| Immune Deficiency Foundation

Understanding primary immunodeficiency (PI)
Understanding PI
The more you understand about primary immunodeficiency (PI), the better you can live with the disease or support others in your life with PI. Learn more about PI, including the various diagnoses and treatment options.
Learn more about PI
Living with PI
Living with PI
Living with primary immunodeficiency (PI) can be challenging, but you’re not alone—many people with PI lead full and active lives. With the right support and resources, you can, too.
Learn more about living with PI
Get involved
Get involved
Be a hero for those with PI. Change lives by promoting primary immunodeficiency (PI) awareness and taking action in your community through advocacy, donating, volunteering, or fundraising.
Get involved today
Advancing research and clinical care
Advancing research and clinical care
Whether you’re a clinician, researcher, or an individual with primary immunodeficiency (PI), IDF has resources to help you advance the field. Get details on surveys, grants, and clinical trials.
View resource details

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Podcast artwork which reads "Bold conversations: Exploring the realities of health access with Dr. Nicole Rochester."

Bold Conversations: The elephant in the exam room

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cropped advocate cover

Spring 2025 IDF ADVOCATE newsletter

Yimmugo

Administration: IVIG
Concentration: 10% (100 mg/mL)
Approved for: Ages 2+

Kedrion distributes Yimmugo in the U.S.

Report side effects/adverse reactions at 1-855-353-7466 or https://www.kedrion.us/ pharmacovigilance/.

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Gaby Talarico in the sunflowers

Thirty-year-old with APS type 1 advocates for her community

Decoding PI: The science of gene therapy and gene editing

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Susan and husband

Susan finds "priceless" support system in the Immune Deficiency Foundation

Thomas and family

Mother details harrowing journey to son's diagnosis and relief of finding the PI community

Lunch & Learn: Post-transplant outcomes for CGD

Undiagnosed podcast thumbnail with person walking in shadow toward light. Text in corner reading "Stories of the long journey to PI diagnosis".

Undiagnosed: Gaslit and Gatekept

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Pink highlighter highlighting the word measles on a page

Study shows Ig therapy is protective against measles

Immune Deficiency Foundation
7550 Teague Road, Suite 220
Hanover, Maryland 21076

P: 410-321-6647