| Immune Deficiency Foundation

Understanding primary immunodeficiency (PI)
Understanding PI
The more you understand about primary immunodeficiency (PI), the better you can live with the disease or support others in your life with PI. Learn more about PI, including the various diagnoses and treatment options.
Learn more about PI
Living with PI
Living with PI
Living with primary immunodeficiency (PI) can be challenging, but you’re not alone—many people with PI lead full and active lives. With the right support and resources, you can, too.
Learn more about living with PI
Get involved
Get involved
Be a hero for those with PI. Change lives by promoting primary immunodeficiency (PI) awareness and taking action in your community through advocacy, donating, volunteering, or fundraising.
Get involved today
Advancing research and clinical care
Advancing research and clinical care
Whether you’re a clinician, researcher, or an individual with primary immunodeficiency (PI), IDF has resources to help you advance the field. Get details on surveys, grants, and clinical trials.
View resource details

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Colemans

Family navigates both CVID and SAD diagnoses

November 07, 2024

Q&A: Antibody deficiencies with Dr. Luke Wall

November 07, 2024

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thumbnail for Decoding PI: Antibody deficiency

Decoding PI: Antibody deficiencies

November 05, 2024

Doctor on computer

Consulting Immunologist Program educates clinicians

October 30, 2024

thumbnail for the ChronicXTwenties podcast which features three circles of Immune Deficiency Foundation colors, and the text "young adulthood, rare disease, and the joy you deserve".

ChronicXTwenties: Heartbreakingly beautiful (Part 2)

October 30, 2024

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Older woman receives vaccine in the upper arm.

Update: What RSV preventatives mean for those with PI

October 24, 2024

Family together smiling

PI diagnosis can pose challenges in obtaining life insurance

October 24, 2024

thumbnail for the ChronicXTwenties podcast which features three circles of Immune Deficiency Foundation colors, and the text "young adulthood, rare disease, and the joy you deserve".

ChronicxTwenties: Heartbreakingly beautiful (Part 1)

October 23, 2024

Listen to podcast

Gloved hand uses tweezers to remove a section of a paper drawing of DNA.

Gene therapy makes headway in PI treatment

October 17, 2024

Blaese awardee targets diagnosis and treatment of Evans syndrome

October 10, 2024

Immune Deficiency Foundation
7550 Teague Road, Suite 220
Hanover, Maryland 21076

P: 410-321-6647