| Immune Deficiency Foundation

Understanding primary immunodeficiency (PI)
Understanding PI
The more you understand about primary immunodeficiency (PI), the better you can live with the disease or support others in your life with PI. Learn more about PI, including the various diagnoses and treatment options.
Learn more about PI
Living with PI
Living with PI
Living with primary immunodeficiency (PI) can be challenging, but you’re not alone—many people with PI lead full and active lives. With the right support and resources, you can, too.
Learn more about living with PI
Get involved
Get involved
Be a hero for those with PI. Change lives by promoting primary immunodeficiency (PI) awareness and taking action in your community through advocacy, donating, volunteering, or fundraising.
Get involved today
Advancing research and clinical care
Advancing research and clinical care
Whether you’re a clinician, researcher, or an individual with primary immunodeficiency (PI), IDF has resources to help you advance the field. Get details on surveys, grants, and clinical trials.
View resource details

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Chapter 15: Diseases of Immune Dysregulation: STAT1 and STAT3 Gain of Function

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Chapter 16: Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy and Autoimmune Polyglandular Syndrome Type-1

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Chapter 17: Autoimmune Lymphoproliferative Syndrome and Related Disorders

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Chapter 18: Hemophagocytic Lymphohistiocytosis and EBV Susceptibility

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Chapter 19: Immune Dysregulation, Enteropathy, and Colitis

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Chapter 20: Hyper IgE Syndromes (HIES): STAT3 Loss of Function, DOCK8 Deficiency and Others

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Chapter 21: Chronic Granulomatous Disease and Other Phagocyte Disorders, Leukocyte Adhesion Deficiency and Neutropenia

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Chapter 22: Complement Deficiencies

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Chapter 23: Innate Immune Defects

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Chapter 24: Inheritance

Immune Deficiency Foundation
7550 Teague Road, Suite 220
Hanover, Maryland 21076

P: 410-321-6647